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641px){._headerBrand_gf886_49{overflow:hidden}._title_gf886_75{min-width:0}._titleMain_gf886_83,._titleSub_gf886_85{overflow:hidden;text-overflow:ellipsis;white-space:nowrap}._headerTabs_gf886_97{position:absolute;left:50%;top:50%;transform:translate(-50%,-50%);z-index:2;display:flex;justify-content:center;align-items:center;width:max-content;max-width:min(100%,calc(100vw - 32px));min-width:0;pointer-events:auto}._headerLogo_gf886_127{flex:1 1 0;display:flex;justify-content:flex-end;align-items:flex-end;min-width:0;z-index:0}._topNav_gf886_145{padding:3px;gap:3px}._navTab_gf886_155{padding:5px 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641px){._companyLogoBox_gf886_231{width:min(184px,30vw);height:44px;padding:0}}._topNav_gf886_145{display:flex;align-items:center;gap:4px;border:1px solid var(--border);border-radius:999px;padding:4px;background:#f8fafc}@media (max-width: 640px){._appHeader_gf886_19{display:grid;grid-template-columns:1fr;grid-template-areas:"brand" "tabs";gap:7px;padding:8px 200px 8px 12px;min-height:0;position:relative;align-content:start;max-width:100%}._headerBrand_gf886_49{grid-area:brand;flex:unset;padding-right:0}._headerTabs_gf886_97{grid-area:tabs;position:static;left:auto;top:auto;transform:none;z-index:auto;width:auto;max-width:100%;justify-self:start;justify-content:flex-start;min-width:0}._topNav_gf886_145{flex-wrap:wrap;max-width:100%}._headerLogo_gf886_127{position:absolute;top:8px;right:8px;width:auto;max-width:calc(100% - 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#0f172a14}._title_gf886_75{display:flex;flex-direction:column;gap:1px}._titleMain_gf886_83{font-size:14px;font-weight:700;line-height:1.2}._titleSub_gf886_85{font-size:11px;line-height:1.3;color:var(--muted)}._actions_gf886_595{display:flex;gap:8px}._main_gf886_605{flex:1;min-height:0;min-width:0;display:grid;gap:10px;padding:10px}@media (max-width: 640px){._main_gf886_605{padding:8px;gap:8px}}._mainDesign_gf886_637{grid-template-columns:minmax(360px,40%) minmax(0,1fr)}@media (max-width: 1280px) and (min-width: 1025px){._mainDesign_gf886_637{grid-template-columns:minmax(320px,42%) minmax(0,1fr)}}@media (max-width: 1024px){._mainDesign_gf886_637{grid-template-columns:1fr}}._mainResults_gf886_669{grid-template-columns:1fr;align-content:start}._left_gf886_679,._center_gf886_681,._right_gf886_683{min-height:0;min-width:0;width:100%}._resultsMain_gf886_695{grid-column:1;width:100%;min-width:0}._resultsHeaderExport_gf886_707{white-space:nowrap;flex-shrink:0}._button_gf886_717{border:1px solid var(--border);background:#fff;border-radius:10px;padding:10px 12px;cursor:pointer;font-size:13px}._button_gf886_717:disabled{opacity:.6;cursor:not-allowed}._primary_gf886_745{background:#2b6cff;border-color:#2b6cff;color:#fff}._secondaryDanger_gf886_757{margin-top:10px;padding:8px 10px;font-size:12px;color:#991b1b;border-color:#f3c3c3;background:#fff6f6}._textarea_gf886_775{width:100%;max-width:100%;min-width:0;height:120px;resize:none;border:1px solid var(--border);border-radius:8px;padding:8px 10px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:12px;line-height:1.4}._resetMini_gf886_805{margin:0;height:28px;padding:0 10px;font-size:11px;line-height:1;display:inline-flex;align-items:center;justify-content:center;align-self:center}._secondaryMini_gf886_829{padding:5px 9px;font-size:11px;color:#334155}._metricsRow_gf886_841{margin-top:10px;display:grid;grid-template-columns:1fr 1fr 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10px;border-radius:8px;font-size:12px;font-weight:700;line-height:1;display:inline-flex;align-items:center;justify-content:center;white-space:nowrap}._projectTypeDesignButton_gf886_975:disabled{background:#d1d5db;border-color:#d1d5db;color:#6b7280;cursor:not-allowed;opacity:1}._projectTypeLabel_gf886_1027{font-size:12px;font-weight:600;color:var(--muted);white-space:nowrap}._projectTypeToggle_gf886_1041{display:flex;flex-wrap:wrap;align-items:center;gap:8px;min-width:0}._projectTypeToggle_gf886_1041 ._methodToggleButton_gf886_1057{box-sizing:border-box;flex:0 0 110px;width:110px;height:32px;min-height:32px;max-height:32px;padding:0 6px;border-radius:8px;font-size:12px;font-weight:600;line-height:1;display:inline-flex;align-items:center;justify-content:center;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}._mutagenesisMain_gf886_1097{grid-template-columns:1fr;align-content:stretch;min-height:0}._mutagenesisView_gf886_1109{display:flex;flex-direction:column;gap:10px;min-width:0;min-height:0;width:100%;height:100%}._mutagenesisLayout_gf886_1129{display:grid;grid-template-columns:minmax(320px,.3fr) minmax(0,.7fr);gap:10px;min-height:0;flex:1;width:100%;align-items:stretch}@media (max-width: 1280px) and (min-width: 1025px){._mutagenesisLayout_gf886_1129{grid-template-columns:minmax(300px,30%) minmax(0,1fr)}}@media (max-width: 1024px){._mutagenesisLayout_gf886_1129{grid-template-columns:1fr}}._mutagenesisPanel_gf886_1173{min-width:0;width:100%}._mutagenesisViewer_gf886_1183{min-width:0;width:100%;min-height:0}._mutagenesisViewerEmpty_gf886_1195{display:flex;align-items:center;justify-content:center;min-height:240px;padding:24px;font-size:12px;color:var(--muted);text-align:center;line-height:1.5}._mutagenesisViewerGrid_gf886_1219{display:grid;grid-template-columns:minmax(208px,280px) minmax(0,1fr);gap:10px;align-items:stretch}@media (max-width: 768px){._mutagenesisViewerGrid_gf886_1219{grid-template-columns:1fr}}._circularMapCard_gf886_1245,._linearSequenceCard_gf886_1247{min-height:0;min-width:0;height:100%}._circularMapCard_gf886_1245{display:flex;flex-direction:column;margin-bottom:0}._circularMapCardBodyWrap_gf886_1271{flex:1;display:flex;flex-direction:column;min-height:0;padding:0}._circularMapCardContent_gf886_1287{display:flex;align-items:center;justify-content:center;flex:1;min-height:0;height:100%;padding:4px 8px}._circularMapCardBody_gf886_1271{display:flex;align-items:center;justify-content:center;flex:1 1 auto;min-height:0;padding:0}._mutagenesisEditRow_gf886_1325{display:grid;grid-template-columns:minmax(0,2fr) minmax(260px,1fr);gap:8px;margin-top:8px;align-items:start}._mutagenesisEditRowSingle_gf886_1341{grid-template-columns:1fr}@media (max-width: 900px){._mutagenesisEditRow_gf886_1325{grid-template-columns:1fr}}._mutagenesisMutationEditCard_gf886_1361{margin-top:0;width:100%;margin-bottom:0;min-width:0}._mutagenesisMutationEditCardBody_gf886_1375{padding:8px 10px}._mutationSummaryCard_gf886_1383{margin-top:0;width:100%;margin-bottom:0;min-width:0}._mutationSummaryCardBody_gf886_1397{padding:8px 10px}._mutationSummaryGrid_gf886_1405{display:flex;flex-direction:column;gap:4px}._mutationSummaryRow_gf886_1417{display:grid;grid-template-columns:minmax(120px,38%) minmax(0,1fr);gap:8px;font-size:12px;line-height:1.35}._mutationSummaryLabel_gf886_1433{color:var(--muted);font-weight:600}._mutationSummaryValue_gf886_1443{color:#0f172a;word-break:break-word;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:11px}._mutationAppliedBanner_gf886_1459{margin-bottom:6px;padding:6px 8px;border:1px solid #86efac;border-radius:8px;background:#ecfdf5;font-size:12px;font-weight:600;color:#166534;line-height:1.35}._mutationAppliedBannerHint_gf886_1483{margin-top:2px;font-size:11px;font-weight:500;color:#15803d}._mutationSummaryCompact_gf886_1497{font-size:12px;line-height:1.45;color:#0f172a;word-break:break-word}._mutationSummaryOrfImpact_gf886_1511{margin-top:4px;font-size:11px;line-height:1.4;color:#1d4ed8;word-break:break-word}._mutationSummaryOrfImpactBlock_gf886_1527{margin-top:6px;padding-top:6px;border-top:1px solid #e2e8f0}._mutationSummaryOrfImpactHeading_gf886_1539{font-size:11px;font-weight:600;color:var(--muted);line-height:1.35}._mutationSummaryOrfImpactLine_gf886_1553{font-size:11px;line-height:1.4;color:#1d4ed8;word-break:break-word}._mutationSummaryOrfWarning_gf886_1567{margin-top:2px;font-size:11px;line-height:1.4;color:#b45309;word-break:break-word}._sequenceLineBody_gf886_1583{display:flex;flex:1;flex-direction:column;gap:1px;min-width:0}._sequenceCoordinateRowEmphasized_gf886_1599{background:#2563eb08;border-radius:3px}._orfLaneLabelCol_gf886_1609{display:flex;align-items:center;padding:0 4px 0 0;font-size:10px;font-weight:600;line-height:1.35;color:#475569;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;-webkit-user-select:none;user-select:none;border:none;background:transparent;text-align:left;font-family:inherit}._orfLaneLabelColSelectable_gf886_1645{cursor:pointer;border-radius:3px}._orfLaneLabelColSelectable_gf886_1645:hover{text-decoration:underline;background:#2563eb0f}._orfLaneLabelColSelectable_gf886_1645:focus-visible{outline:2px solid rgba(37,99,235,.35);outline-offset:1px}._orfLaneLabelColEmphasized_gf886_1675{color:#1d4ed8;font-weight:700}._orfLaneLabelColMuted_gf886_1685{color:#475569;font-weight:600}._sequenceLineUnifiedGrid_gf886_1695{display:grid;width:max-content;max-width:100%;align-items:center;row-gap:1px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:14px;line-height:1.45;letter-spacing:0;--seq-editor-base-line-height: 1.65;--seq-editor-base-padding-y: 2px;--seq-editor-base-width: 1.4ch}._aminoAcidReferenceLabel_gf886_1727{z-index:1;position:relative;display:flex;align-items:center;justify-content:center;min-width:0;max-width:100%;min-height:16px;overflow:hidden;text-overflow:ellipsis;text-align:center;font-size:11px;font-weight:600;line-height:1.45;color:#2563eb;pointer-events:auto;white-space:nowrap;-webkit-user-select:none;user-select:none;box-sizing:border-box;border-left:1px solid rgba(71,85,105,.32);border-right:1px solid rgba(71,85,105,.32)}._aminoAcidReferenceLabelSelectable_gf886_1775{cursor:pointer}._aminoAcidReferenceLabelSelectable_gf886_1775:hover{text-decoration:underline;background:#2563eb0f}._orfAminoAcidRowStack_gf886_1793{display:flex;flex-direction:column;gap:1px;margin-bottom:2px}._orfAminoAcidUnifiedRow_gf886_1807{display:grid;width:max-content;max-width:100%;align-items:center;min-height:14px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:9px;line-height:1.3;letter-spacing:0}._orfAminoAcidUnifiedRow_gf886_1807 ._aminoAcidReferenceLabel_gf886_1727{color:#64748b}._orfAminoAcidUnifiedRowEmphasized_gf886_1841 ._aminoAcidReferenceLabel_gf886_1727,._orfAminoAcidUnifiedRowEmphasized_gf886_1841 ._orfLaneLabelCol_gf886_1609{color:#3b82f6}._orfAminoAcidUnifiedRowEmphasized_gf886_1841 ._orfLaneLabelCol_gf886_1609{font-weight:700}._orfDnaRowAligned_gf886_1859{display:flex;align-items:flex-start}._orfLaneLabelColSpacer_gf886_1869{flex:0 0 52px;min-width:52px}._orfCodonBoundaryMarker_gf886_1879{align-self:stretch;justify-self:start;width:0;min-height:100%;border-left:1px solid rgba(71,85,105,.38);pointer-events:none;z-index:0}._orfCodonBoundaryMarkerEmphasized_gf886_1899{border-left-color:#1d4ed87a}._orfCodonBoundaryMarkerMuted_gf886_1907{border-left-color:#47556961}._aminoAcidReferenceLabelEmphasized_gf886_1915{color:#1d4ed8;font-weight:700;border-left-color:#1d4ed86b;border-right-color:#1d4ed86b}._aminoAcidReferenceLabelBoundary_gf886_1929{border-left:none;border-right:none}._aminoAcidReferenceLabelMuted_gf886_1939{color:#334155;font-weight:600;border-left-color:#47556952;border-right-color:#47556952}._sequenceLineUnifiedGrid_gf886_1695 ._sequenceBase_gf886_1953{line-height:1.65;letter-spacing:0;width:auto;min-width:0;max-width:none}._orfReferenceGap_gf886_1969{background:#3b82f61f;color:#3b82f61f}._orfReferenceOptionRow_gf886_1981{display:flex;align-items:center;gap:8px;margin-bottom:8px;font-size:12px;color:#0f172a}._orfReferenceOptionLabel_gf886_1999{flex:0 0 auto;color:var(--muted)}._orfReferenceLengthInput_gf886_2009{width:96px}._orfReferenceInfo_gf886_2017{font-size:11px;color:var(--muted);line-height:1.35}._orfReferenceHighlight_gf886_2029{background:#3b82f614;color:#0f172a}._orfReferenceHighlightEmphasized_gf886_2039{background:#2563eb24;color:#0f172a}._orfReferenceHighlightMiddle_gf886_2049,._orfReferenceHighlightEmphasizedMiddle_gf886_2051{border-radius:0}._orfReferenceHighlightStart_gf886_2059{border-radius:3px 0 0 3px}._orfReferenceHighlightEnd_gf886_2067{border-radius:0 3px 3px 0}._orfReferenceHighlightSingle_gf886_2075{border-radius:3px}._orfReferenceHighlightEmphasizedStart_gf886_2083{border-radius:3px 0 0 3px}._orfReferenceHighlightEmphasizedEnd_gf886_2091{border-radius:0 3px 3px 0}._orfReferenceHighlightEmphasizedSingle_gf886_2099{border-radius:3px}._orfReferenceHighlightSubtle_gf886_2107{background:#3b82f60d;color:#0f172a}._orfReferenceHighlightSubtleMiddle_gf886_2117{border-radius:0}._orfReferenceHighlightSubtleStart_gf886_2125{border-radius:3px 0 0 3px}._orfReferenceHighlightSubtleEnd_gf886_2133{border-radius:0 3px 3px 0}._orfReferenceHighlightSubtleSingle_gf886_2141{border-radius:3px}._orfReferenceGapSubtle_gf886_2149{background:#3b82f60d;color:#3b82f60d}._orfReferenceGapEmphasized_gf886_2159{background:#2563eb33;color:#2563eb33}._mutatedPlasmidSequenceCard_gf886_2169{width:100%;margin-bottom:0}._mutatedPlasmidSequenceCardBody_gf886_2179{padding:10px 12px}._mutatedPlasmidSequenceHeaderActions_gf886_2187{display:flex;align-items:center;gap:8px}._mutatedPlasmidSequenceMeta_gf886_2199{margin-bottom:8px;font-size:12px;color:#64748b}._mutatedPlasmidSequenceScroll_gf886_2211{max-height:320px;overflow:auto;border:1px solid var(--border);border-radius:8px;padding:8px 10px;background:#fafafa}._mutatedSequencePreviewCard_gf886_2229{margin-top:8px;width:100%;margin-bottom:0}._mutatedSequencePreviewCardBody_gf886_2241{padding:8px 10px}._mutatedSequencePreviewScroll_gf886_2249{max-height:100px;overflow:auto;border:1px solid var(--border);border-radius:8px;padding:6px 8px;background:#fafafa}._mutatedSequencePreviewLine_gf886_2267{display:flex;gap:10px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:12px;line-height:1.65;white-space:pre}._mutatedSequencePreviewLineNumber_gf886_2287{flex:0 0 52px;text-align:right;color:var(--muted)}._mutatedSequencePreviewBases_gf886_2299{color:#0f172a;word-break:break-all}._appliedMutationSubstitutionHighlight_gf886_2309{background:#fef3c7;color:#92400e}._appliedMutationSubstitutionHighlightMiddle_gf886_2319{border-radius:0}._appliedMutationSubstitutionHighlightStart_gf886_2327{border-radius:3px 0 0 3px}._appliedMutationSubstitutionHighlightEnd_gf886_2335{border-radius:0 3px 3px 0}._appliedMutationSubstitutionHighlightSingle_gf886_2343{border-radius:3px}._appliedMutationSubstitutionGap_gf886_2351{background:#f59e0b;color:#f59e0b}._ezchangeMultiMutationHighlight_gf886_2361{background:#dbeafe;color:#1e3a8a}._ezchangeMultiMutationHighlightMiddle_gf886_2371{border-radius:0}._ezchangeMultiMutationHighlightStart_gf886_2379{border-radius:3px 0 0 3px}._ezchangeMultiMutationHighlightEnd_gf886_2387{border-radius:0 3px 3px 0}._ezchangeMultiMutationHighlightSingle_gf886_2395{border-radius:3px}._ezchangeMultiMutationGap_gf886_2403{background:#60a5fa;color:#60a5fa}._ezchangeMultiMutationHighlightActive_gf886_2413{background:#bfdbfe;color:#1d4ed8;box-shadow:inset 0 0 0 1px #2563eb}._ezchangeMultiMutationHighlightActiveMiddle_gf886_2425{border-radius:0}._ezchangeMultiMutationHighlightActiveStart_gf886_2433{border-radius:3px 0 0 3px}._ezchangeMultiMutationHighlightActiveEnd_gf886_2441{border-radius:0 3px 3px 0}._ezchangeMultiMutationHighlightActiveSingle_gf886_2449{border-radius:3px}._ezchangeMultiMutationGapActive_gf886_2457{background:#2563eb;color:#2563eb}._ezchangeMultiMutationLabel_gf886_2467{color:#1d4ed8;font-size:13px;font-weight:600}._ezchangeMultiMutationLabelActive_gf886_2479{color:#1e40af;font-weight:700}._ezchangeMultiMutationMapArc_gf886_2489{fill:none;stroke:#60a5fa;stroke-width:4;stroke-linecap:round;pointer-events:none}._ezchangeMultiMutationMapArcActive_gf886_2505{stroke:#2563eb;stroke-width:6}._ezchangeMultiMutationMapTick_gf886_2515{stroke:#60a5fa;stroke-width:2;stroke-linecap:round;pointer-events:none}._ezchangeMultiMutationMapTickActive_gf886_2529{stroke:#2563eb;stroke-width:3}._ezchangeMultiMutationMapLabel_gf886_2539{fill:#1d4ed8;font-size:13px;font-weight:600;pointer-events:none}._ezchangeMultiMutationMapLabelActive_gf886_2553{fill:#1e40af;font-weight:700}._appliedMutationDeletionHighlight_gf886_2563{background:#fee2e2;color:#991b1b;text-decoration:line-through;text-decoration-color:#dc2626}._appliedMutationDeletionHighlightMiddle_gf886_2577{border-radius:0}._appliedMutationDeletionHighlightStart_gf886_2585{border-radius:3px 0 0 3px}._appliedMutationDeletionHighlightEnd_gf886_2593{border-radius:0 3px 3px 0}._appliedMutationDeletionHighlightSingle_gf886_2601{border-radius:3px}._appliedMutationDeletionGap_gf886_2609{background:#f87171;color:#f87171}._appliedMutationInsertionCaret_gf886_2619{display:inline-block;position:relative;width:2px;height:1.15em;margin:0 1px;background:#16a34a;vertical-align:baseline}._appliedMutationInsertionCaret_gf886_2619:before,._appliedMutationInsertionCaret_gf886_2619:after{content:"";position:absolute;left:50%;transform:translate(-50%);border-left:4px solid transparent;border-right:4px solid transparent}._appliedMutationInsertionCaret_gf886_2619:before{top:-5px;border-bottom:5px solid #16a34a}._appliedMutationInsertionCaret_gf886_2619:after{bottom:-5px;border-top:5px solid #16a34a}._appliedMutationInsertionLabel_gf886_2679{padding:0 4px;border-radius:4px;background:#dcfce7;color:#166534;font-size:10px;font-weight:600;line-height:1.4;white-space:nowrap}._appliedMutationSubstitutionLabel_gf886_2701{padding:0 5px;border-radius:4px;background:#fef3c7;color:#92400e;border:1px solid #fcd34d;font-size:10px;white-space:nowrap}._appliedMutationDeletionLabel_gf886_2721{padding:0 5px;border-radius:4px;background:#fee2e2;color:#991b1b;border:1px solid #fca5a5;font-size:10px;white-space:nowrap}._mutatedSequencePreviewCollapsed_gf886_2741{font-size:11px;color:var(--muted);line-height:1.35}._mutatedSequencePreviewBase_gf886_2299{display:inline-block}._mutatedSequencePreviewChanged_gf886_2761{border-radius:2px;padding:0 1px}._mutatedSequencePreviewInsertion_gf886_2771{background:#dcfce7;color:#166534}._mutatedSequencePreviewSubstitution_gf886_2781{background:#fef3c7;color:#92400e}._mutatedSequencePreviewDeletion_gf886_2791{background:#fee2e2;color:#991b1b;text-decoration:underline}._circularMapSvg_gf886_2803{width:100%;max-width:208px;height:auto}._mutagenesisCircularRing_gf886_2815{stroke:#2563eb;stroke-width:3}._mutagenesisCircularRingEmpty_gf886_2825{stroke:#cbd5e1;stroke-width:3}._mutagenesisOrfMapArc_gf886_2835{fill:none;stroke-linecap:round;pointer-events:stroke}._mutagenesisOrfMapArcDefault_gf886_2847{stroke:#475569;stroke-width:2.5;opacity:.9}._mutagenesisOrfMapArcActive_gf886_2859{stroke:#2563eb;stroke-width:3.25;opacity:1}._mutagenesisOriginTick_gf886_2871{stroke:#1d4ed8;stroke-width:2}._mutagenesisOriginMarker_gf886_2881{fill:#1d4ed8}._mutagenesisCircularLength_gf886_2889{font-size:13px;font-weight:700;fill:#0f172a}._mutagenesisCircularLengthEmpty_gf886_2901{font-size:13px;font-weight:700;fill:#94a3b8}._sequenceEditorEmpty_gf886_2913{display:flex;align-items:center;justify-content:center;min-height:calc(var(--seq-editor-scroll-padding, 4px) + var(--seq-editor-visible-rows, 10) * (var(--seq-editor-row-font-size, 13px) * var(--seq-editor-row-line-height, 1.7) + var(--seq-editor-row-gap, 6px)));padding:16px;font-size:12px;color:var(--muted);text-align:center;line-height:1.5}._linearSequenceScroll_gf886_2947{--seq-editor-visible-rows: 10;--seq-editor-row-font-size: 13px;--seq-editor-row-line-height: 1.7;--seq-editor-row-gap: 6px;--seq-editor-scroll-padding: 4px;max-height:calc(var(--seq-editor-scroll-padding) + var(--seq-editor-visible-rows) * (var(--seq-editor-row-font-size) * var(--seq-editor-row-line-height) + var(--seq-editor-row-gap)));overflow:auto;padding:2px 0;-webkit-user-select:none;user-select:none;--seq-editor-base-width: 1.4ch;--seq-editor-base-group-gap: .65ch}._linearSequenceCard_gf886_1247 ._linearSequenceScroll_gf886_2947 ._sequenceLine_gf886_1583{display:flex;gap:10px;width:fit-content;max-width:100%;margin-bottom:6px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:13px;line-height:1.7;white-space:pre}._linearSequenceCard_gf886_1247 ._linearSequenceScroll_gf886_2947 ._sequenceLineNumber_gf886_3011{flex:0 0 52px;text-align:right;color:var(--muted);-webkit-user-select:none;user-select:none}._linearSequenceCard_gf886_1247 ._linearSequenceScroll_gf886_2947 ._sequenceLineBody_gf886_1583{flex:0 1 auto;min-width:0}._linearSequenceCard_gf886_1247 ._linearSequenceScroll_gf886_2947 ._sequenceLineBases_gf886_3035{color:#0f172a;line-height:1.65;font-size:14px}._linearSequenceCard_gf886_1247 ._sequenceBase_gf886_1953{line-height:1.65;letter-spacing:0;width:var(--seq-editor-base-width, 1.4ch);min-width:var(--seq-editor-base-width, 1.4ch);max-width:var(--seq-editor-base-width, 1.4ch)}._sequenceLine_gf886_1583{display:flex;gap:12px;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:12px;line-height:1.65;white-space:pre}._sequenceLineNumber_gf886_3011{flex:0 0 48px;text-align:right;color:var(--muted);-webkit-user-select:none;user-select:none}._sequenceLineBasesRow_gf886_3097{position:relative;--seq-editor-base-line-height: 1.65;--seq-editor-base-padding-y: 2px}._sequenceLineBases_gf886_3035{color:#0f172a;letter-spacing:0;line-height:1.6;font-size:12px}._sequenceAnnotationLayerOverlay_gf886_3123{position:absolute;top:0;left:0;right:0;bottom:0;font-size:14px;line-height:1.65;pointer-events:none}._orfSequenceLineWrap_gf886_3145{position:relative;display:inline-block;width:max-content;max-width:100%}._orfMutationOverlayDna_gf886_3159{position:absolute;left:52px;right:0;top:calc(var(--orf-row-count, 0) * 19px);height:calc(1em * var(--seq-editor-base-line-height, 1.65) + 4px);--seq-editor-base-line-height: 1.65;display:flex;align-items:center;font-size:14px;line-height:1.65;pointer-events:none;z-index:2}._orfMutationOverlayBelow_gf886_3189{position:absolute;left:52px;right:0;bottom:0;height:14px;font-size:14px;line-height:1.65;pointer-events:none;z-index:2}._sequenceAnnotationLabel_gf886_3213{display:flex;align-items:center;justify-content:center;margin:0;white-space:nowrap;pointer-events:auto;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:10px;font-weight:600;line-height:1.4}._sequenceAnnotationLabel_gf886_3213._ezchangeMultiMutationLabel_gf886_2467{font-size:13px}._sequenceAnnotationLabelOverlay_gf886_3249{display:inline-flex;width:max-content;min-width:max-content;max-width:none;white-space:nowrap;pointer-events:none;z-index:2}._sequenceMutationLabelAnchor_gf886_3269{position:absolute;top:0;width:0;height:0;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:inherit;line-height:inherit;letter-spacing:0;pointer-events:none;z-index:2}._sequenceMutationLabelAnchor_gf886_3269 ._sequenceAnnotationLabel_gf886_3213{position:absolute;top:0;left:0;transform:translate(-50%);pointer-events:auto}._appliedMutationInsertionMarker_gf886_3313{display:block;position:absolute;top:50%;width:2px;height:calc(1em * var(--seq-editor-base-line-height, 1.65));margin:0;margin-top:calc(-.5em * var(--seq-editor-base-line-height, 1.65));transform:translate(-50%);background:#16a34a;border-radius:1px;pointer-events:none;z-index:2}._appliedMutationInsertionMarker_gf886_3313:before{content:"";position:absolute;top:-5px;left:50%;transform:translate(-50%);border-left:4px solid transparent;border-right:4px solid transparent;border-bottom:5px solid #16a34a}._sequenceBaseGroupSpace_gf886_3365{display:inline-block;width:var(--seq-editor-base-group-gap, .65ch);min-width:var(--seq-editor-base-group-gap, .65ch);max-width:var(--seq-editor-base-group-gap, .65ch);-webkit-user-select:none;user-select:none;vertical-align:baseline;padding:0;margin:0;box-sizing:border-box}._sequenceInsertionGroupGap_gf886_3389{cursor:pointer}._sequenceBaseGroupGap_gf886_3397{align-self:stretch;min-height:100%;padding:2px 0;box-sizing:border-box}._selectionBandGap_gf886_3411,._selectionBandGapPreview_gf886_3413{margin:0;padding:2px 0;line-height:1.6;box-sizing:border-box}._selectionBandGap_gf886_3411{background:#1d4ed8;color:#1d4ed8}._selectionBandGapPreview_gf886_3413{background:#60a5fa;color:#60a5fa}._sequenceBase_gf886_1953{display:inline-block;position:relative;width:var(--seq-editor-base-width, 1.4ch);min-width:var(--seq-editor-base-width, 1.4ch);max-width:var(--seq-editor-base-width, 1.4ch);text-align:center;padding:2px 0;margin:0;cursor:pointer;-webkit-user-select:none;user-select:none;vertical-align:baseline;border:none;box-shadow:none;box-sizing:border-box;line-height:1.6;font-weight:400;letter-spacing:0;transition:background-color 80ms ease,color 80ms ease}._sequenceBaseGridCell_gf886_3489{position:relative;display:flex;align-items:center;justify-content:center;width:auto;min-width:0;max-width:none;justify-self:stretch}._selectionRangeHighlight_gf886_3511{background:#1d4ed8;color:#fff}._selectionRangeHighlightMiddle_gf886_3521{border-radius:0}._selectionRangeHighlightStart_gf886_3529{border-radius:3px 0 0 3px}._selectionRangeHighlightEnd_gf886_3537{border-radius:0 3px 3px 0}._selectionRangeHighlightSingle_gf886_3545{border-radius:3px}._selectionRangePreview_gf886_3553{background:#60a5fa;color:#fff}._selectionRangePreviewMiddle_gf886_3563{border-radius:0}._selectionRangePreviewStart_gf886_3571{border-radius:3px 0 0 3px}._selectionRangePreviewEnd_gf886_3579{border-radius:0 3px 3px 0}._selectionRangePreviewSingle_gf886_3587{border-radius:3px}._insertionPointCaret_gf886_3595,._insertionPointCaretInline_gf886_3625{display:block;position:absolute;top:50%;left:calc(100% - 1px);width:2px;height:calc(1em * var(--seq-editor-base-line-height, 1.65));margin:0;margin-top:calc(-.5em * var(--seq-editor-base-line-height, 1.65));background:#2563eb;border-radius:1px;pointer-events:none;z-index:1}._insertionPointCaretInline_gf886_3625:before,._insertionPointCaretInline_gf886_3625:after{content:"";position:absolute;left:50%;transform:translate(-50%);width:6px;height:2px;background:#2563eb;border-radius:1px}._insertionPointCaretInline_gf886_3625:before{top:-2px}._insertionPointCaretInline_gf886_3625:after{bottom:-2px}._insertionPointCaret_gf886_3595:before,._insertionPointCaret_gf886_3595:after{content:"";position:absolute;left:50%;transform:translate(-50%);width:6px;height:2px;background:#2563eb;border-radius:1px}._insertionPointCaret_gf886_3595:before{top:-2px}._insertionPointCaret_gf886_3595:after{bottom:-2px}._orfTrackLabelCol_gf886_3735{display:block;min-width:0;-webkit-user-select:none;user-select:none}._orfTrackStack_gf886_3747{display:flex;flex-direction:column;gap:2px;margin-bottom:4px}._orfTrackRowGrid_gf886_3761{display:grid;width:max-content;max-width:100%;align-items:stretch;min-height:14px}._orfRegionTrackSegment_gf886_3777{align-self:stretch;display:flex;align-items:center;min-height:12px;padding:0 4px;overflow:hidden;font-size:9px;font-weight:600;line-height:1.2;color:#1e40af;white-space:nowrap;text-overflow:ellipsis;background:#3b82f624;border-radius:2px;-webkit-user-select:none;user-select:none;pointer-events:auto}._orfRegionTrackSegmentEmphasized_gf886_3815{color:#1e3a8a;background:#2563eb38}._sequenceMutationBelowRow_gf886_3825{position:relative;height:14px;margin-top:2px}._sequenceMutationBelowLayer_gf886_3837{position:relative;height:14px;font-size:14px;line-height:1.65;pointer-events:none}._mutagenesisSelectionArc_gf886_3853{fill:none;stroke:#2563eb;stroke-width:10;stroke-linecap:round;pointer-events:none}._mutagenesisSelectionMapMarker_gf886_3869{fill:#2563eb;stroke:#fff;stroke-width:2;pointer-events:none}._mutagenesisWarning_gf886_3883{margin-top:10px;padding:8px 10px;border:1px solid #f0d18a;background:#fff8e8;border-radius:10px;font-size:12px;color:#7c5a00;line-height:1.45}._mutagenesisSequenceInfo_gf886_3905{margin-top:12px;display:flex;flex-direction:column;gap:6px;padding:10px 12px;border:1px solid var(--border);border-radius:10px;background:#f9fafb}._mutagenesisInfoRow_gf886_3927{display:flex;flex-wrap:wrap;gap:6px;font-size:12px;line-height:1.4}._mutagenesisInfoLabel_gf886_3943{color:var(--muted);font-weight:600}._mutagenesisInfoValue_gf886_3953{color:#0f172a}._mutagenesisEditEmpty_gf886_3961{font-size:12px;color:var(--muted);line-height:1.4}._mutagenesisEditBody_gf886_3973{display:flex;flex-direction:column;gap:6px}._mutagenesisEditSummary_gf886_3985{font-size:12px;font-weight:600;color:#0f172a;line-height:1.35;word-break:break-word}._mutagenesisEditOrfContext_gf886_4001{font-size:12px;color:#334155;line-height:1.35}._mutagenesisCodingReferenceRow_gf886_4013{display:flex;flex-wrap:wrap;align-items:center;gap:8px 10px;min-width:0}._mutagenesisCodingReferenceLabel_gf886_4029{flex-shrink:0;font-size:12px;font-weight:600;color:#64748b}._mutagenesisCodingReferenceValue_gf886_4043{font-size:12px;color:#334155;line-height:1.4}._mutagenesisCodingReferenceSelect_gf886_4055{min-width:0;flex:1 1 180px;max-width:100%;padding:6px 8px;border:1px solid #cbd5e1;border-radius:8px;background:#fff;font-size:12px;color:#0f172a}._mutagenesisEditOrfReference_gf886_4079{margin-top:4px;padding-top:6px;border-top:1px solid #e2e8f0}._mutagenesisEditOrfReferenceHeading_gf886_4091{font-size:11px;font-weight:600;color:var(--muted);line-height:1.35}._mutagenesisEditOrfReferenceLine_gf886_4105{font-size:11px;color:#334155;line-height:1.35}._mutagenesisEditOrfReferenceTranslation_gf886_4117{font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace;font-size:11px;color:#0f172a;line-height:1.45;white-space:pre}._mutagenesisEditInlineRow_gf886_4135{display:flex;align-items:center;gap:8px;flex-wrap:wrap;min-width:0}._mutagenesisEditLabel_gf886_4151{flex-shrink:0;font-size:12px;font-weight:600;color:var(--muted)}._mutagenesisEditInput_gf886_4165{flex:1;min-width:140px;padding:7px 10px;font-size:12px}._mutagenesisEditInlineError_gf886_4179{font-size:11px;color:#b91c1c;line-height:1.35}._mutagenesisEditInlineWarning_gf886_4191{font-size:11px;color:#7c5a00;line-height:1.35}._mutagenesisEditActions_gf886_4203{display:flex;flex-wrap:wrap;gap:6px;align-items:center}._mutagenesisEditButton_gf886_4217{min-width:64px;height:32px;padding:0 14px;box-sizing:border-box;line-height:1;font-size:12px}._mutagenesisEditHint_gf886_4235{font-size:11px;color:var(--muted);line-height:1.35}._ezchangeMultiMutationList_gf886_4247{display:flex;flex-direction:column;gap:6px;margin-top:10px;padding-top:10px;border-top:1px solid #e2e8f0}._ezchangeMultiMutationListHeader_gf886_4265{display:flex;align-items:center;justify-content:space-between;gap:8px}._ezchangeMultiMutationListTitle_gf886_4279{font-size:12px;font-weight:600;color:#0f172a}._ezchangeMultiMutationListWarning_gf886_4291{font-size:12px;color:#b45309;line-height:1.35}._ezchangeMultiMutationListTable_gf886_4303{display:flex;flex-direction:column;gap:4px;font-size:12px}._ezchangeMultiMutationListHead_gf886_4265,._ezchangeMultiMutationListRow_gf886_4319{display:grid;grid-template-columns:42px minmax(56px,.7fr) minmax(0,2fr) 48px minmax(108px,.9fr);gap:8px;align-items:center}._ezchangeMultiMutationListHead_gf886_4265{color:#64748b;font-weight:600}._ezchangeMultiMutationListBody_gf886_4343{display:flex;flex-direction:column;gap:4px}._ezchangeMultiMutationListRow_gf886_4319{padding:4px 0;border-top:1px solid #f1f5f9}._ezchangeMultiMutationListRowEditing_gf886_4365{background:#f8fafc}._ezchangeMultiMutationListId_gf886_4373{font-weight:600;color:#0f172a}._ezchangeMultiMutationListChange_gf886_4383{word-break:break-all}._ezchangeMultiMutationListActions_gf886_4391,._ezchangeMultiMutationListActionsHead_gf886_4393{display:flex;gap:6px;justify-content:flex-end}._ezchangeMultiMutationListActionButton_gf886_4405{border:none;background:transparent;color:#2563eb;font-size:12px;font-weight:600;cursor:pointer;padding:0}._ezchangeMultiMutationListActionButton_gf886_4405:hover{text-decoration:underline}._searchInputRow_gf886_4433{display:flex;align-items:center;gap:6px}._searchInputRow_gf886_4433 ._input_gf886_921{flex:1;min-width:0}._searchMatchNavButton_gf886_4455{flex:0 0 32px;width:32px;min-width:32px;padding:7px 0;font-size:14px;line-height:1;font-weight:600}._mutagenesisViewerCardHeader_gf886_4475{min-height:40px;box-sizing:border-box;flex-wrap:nowrap}._mutagenesisViewerCardHeader_gf886_4475 ._titleRight_gf886_4487,._mutagenesisViewerCardHeader_gf886_4475>:last-child{flex-shrink:0}._clearSelectionGhost_gf886_4497{padding:3px 8px;font-size:11px;font-weight:500;line-height:1.2;color:#475569;background:#fff;border:1px solid var(--border);border-radius:6px;cursor:pointer;white-space:nowrap}._clearSelectionGhost_gf886_4497:hover:not(:disabled){background:#f8fafc;border-color:#cbd5e1}._clearSelectionGhost_gf886_4497:disabled{opacity:.45;cursor:not-allowed}._searchMatchInfo_gf886_4543{margin-top:8px;font-size:12px;color:var(--muted);line-height:1.45}._searchHighlightMatch_gf886_4557{background:#fef9c3;color:#854d0e;border-radius:2px}._searchHighlightCurrent_gf886_4569{background:#fbbf24;color:#451a03;border-radius:2px}._mutagenesisSearchMapMarker_gf886_4581{fill:#f59e0b;stroke:#fff;stroke-width:1.5}._methodToggle_gf886_1057{display:grid;grid-template-columns:1fr 1fr;gap:8px}._methodToggleButton_gf886_1057{border:1px solid var(--border);background:#fff;border-radius:8px;padding:8px 10px;font-size:12px;font-weight:600;cursor:pointer}._methodToggleButtonActive_gf886_4625{border-color:#2563eb;background:#dbeafe;color:#1d4ed8}._pcrInputStack_gf886_4637{display:flex;flex-direction:column;gap:12px}._pcrPrimerInput_gf886_4649{height:38px;resize:none;line-height:1.2;font-family:ui-monospace,SFMono-Regular,Menlo,Monaco,Consolas,Liberation Mono,Courier New,monospace}._toggles_gf886_4665{display:flex;flex-direction:column;gap:8px;margin-top:8px}._advancedButton_gf886_4679{margin-top:10px;border:none;background:transparent;color:#2b6cff;cursor:pointer;padding:0;font-size:13px}._advancedSettingsHelp_gf886_4699{margin-top:10px;margin-bottom:14px;font-size:12px;line-height:1.45;color:var(--muted)}._advancedSettingsGrid_gf886_4715{display:grid;grid-template-columns:1fr 1fr;gap:10px 12px}._advancedSettingsToggle_gf886_4727{grid-column:1 / -1;padding-top:2px}._advancedBox_gf886_4737{margin-top:8px;border:1px dashed 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